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[중년의뇌] Neurogenesis in the adult human hippocampus

by 변정구 posted Apr 02, 2011
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첨부된 pdf파일은 중년의뇌(바버라 스트로치), 205페이지에 언급된, 1998년 프레드 게이지, 페테르 에릭손의 논문입니다.

논문 제목 : Neurogenesis in the adult human hippocampus





(참고)


http://en.wikipedia.org/wiki/Fred_Gage
http://en.wikipedia.org/wiki/Peter_Eriksson_(neuroscientist)
http://www.braincellsinc.com/
http://howtogetfocused.com/chapters/how-exercise-increases-focus/


http://en.wikipedia.org/wiki/Dentate_gyrus 치아 이랑
http://en.wikipedia.org/wiki/Subgranular_zone

http://en.wikipedia.org/wiki/Bromodeoxyuridine BrdU
http://en.wikipedia.org/wiki/Calbindin Calbindin
http://en.wikipedia.org/wiki/Neuron_specific_enolase NSE
http://en.wikipedia.org/wiki/Enolase Enolase
http://en.wikipedia.org/wiki/Glial_fibrillary_acidic_protein GFAP
http://en.wikipedia.org/wiki/Nestin_(protein) Nestin


http://en.wikipedia.org/wiki/Neural_development
http://en.wikipedia.org/wiki/Neural_development_in_humans
http://en.wikipedia.org/wiki/Neurogenesis
http://en.wikipedia.org/wiki/Neuroplasticity


NeuN : neuronal specific nuclear protein


Fred H. Gage
of the Salk Institute for Biological Studies, La Jolla, California



Phenotypes of proliferating cells in the RMS and DG.


Double-labeled immunofluoresence studies showed that in the RMS most cells were BrdU+/nestin+ (arrow, a) and revealed the presence of GFAP+ filaments (arrow, b) surrounding BrdU+ cells (asterisk, b).


In the DG, BrdU+/nestin+ cells (c) were seen and a few BrdU+/GFAP+ cells could also be found (arrow, d, e). BrdU (red); nestin, GFAP (green).
Faiz et al. BMC Neuroscience 2005 6:26 doi:10.1186/1471-2202-6-26


sgz: hippocampal subgranular zone
RMS : Rostral Migratory Stream
Identity of proliferating cells was determined by double immunolabeling with nestin, GFAP, NeuN and tomato lectin (TL).



The Growth of New Neurons in the Adult Human Brain



http://thebrain.mcgill.ca/flash/capsules/histoire_bleu05.html


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